More than 140 compounds have been isolated from different parts
of Melia herb or neem. All parts of the neem tree as:
·
leaves,
·
flowers,
·
seeds,
·
fruits,
·
roots and
·
bark
have been used traditionally for the treatment of
inflammation, infections, fever, skin diseases and dental disorders.
Among those active constituents, Neem has thirty-one
nortriterpenoids, including 28 limonoids and 3 degraded limonoids, and one
diterpenoid [3], as well as azadirachtin.
ANTI-MICROBIAL AND ANTI-BACTERIAL PROPERTIES OF
AZADIRACHTA INDICA (NEEM)
Among
all the properties and health benefits exerted by Azadirachta indica (Neem) we
shall highlight one, its ability to treat
skin and skin related problems, either as part of poly
herbal anti-acne face wash gels formulations [1], or part of anti-microbial preparations against some
groups of bacteria as Escherichia coli
(E.coli) [2].
Azadirachta indica
(Neem) by itself doesn't seem to be much different from any other plant from
its family and genus, but when we look closer we find some major
differences that may indicate why this plant is so different, its
active constituents, among which we find thirty-one nortriterpenoids,
including 28 limonoids and 3 degraded limonoids, and one diterpenoid [3]. Image right: Neem tree by Wendy Cutler
under Creative Common license (CC BY 2.0).
At
least one study reported how five of those active constituents found in
Melia herb or Azadirachta indica (Neem) showed an important inhibitory
effect on the melanogenesis in the B16 melanoma cells, with results of 74 to 91% reduction of
melanin content at 25 micro G/ml and almost no toxicity to healthy
cells[3], with which Neem becomes one of these plants to be noted for
the development of new drugs based on the active constituents of
this plant.
Neem
leaves are responsible for some already mentioned neem benefits, they are
known to possess immunomodulatory, anti-inflammatory,
antihyperglycaemic, antiulcer, antimalarial, antifungal, antibacterial,
antiviral, antioxidant, antimutagenic and anticarcinogenic properties
[5,7], being one of the most active parts of the plant.
ANTI-GINGIVITIS AND ANTI-PLAQUE PROPERTIES OF NEEM
The use
of Azadirachta indica (neem) for the treatment of dental ailments as gingivitis, plaque and periodontitis have
been reported in India since several decades ago, mainly due to its antiseptic properties
and activity [9].
In a
study of the subject, forty-five subjects with plaque-induced gingivitis divided into three groups
were asked to rinse with 15 ml of mouthwash twice a day.
The
study showed that Azadirachta indica (neem) was as effective in reducing periodontitis as
Chlorhexidine, reducing significantly gingival
bleeding and plaque indices in the non-placebo groups [9].
NEEM FOR CERVICAL CANCER
In, at
least, one study on the antioxidant properties of neem (Azadirachta
indica) in inducing apoptosis of cervical cancer cells, neem
demonstrated to be a potent inducer of apoptosis in biopsies of cervical cancer
patients [10].
NEEM BENEFITS AND SIDE EFFECTS
As with
any other herbs and plants the use of Neem should follow your doctor's advice.
In primates, the use of neem (Azadirachta indica) seed extracts (Praneem)
given orally caused abrogation of pregnancy.
In the
time following treatment, the animals regained their normal cyclicity in
the cycles subsequent to Praneem treatment [1].
PRICE
$96.99/KG OR
$44.08/IB
For more information:
mobile: +2348039721941
contact person: emeaba uche
e-mail: emeabau@yahoo.com
No comments:
Post a Comment